The most important and the most interesting experiments providing scientific support for acupunctural analgesia were studies conducted on humans and animals using endorphin antagonists (e.g. Naloxon, Naltrexone).

As new results indicate, the strong analgesic effect of electro acupuncture in the low-frequency range is due to methionin/encephalin release and in the high-frequency range due to A-dinorphin. At the same time, the higher concentration of the body's own circulating morphins improves the sense of well-being. A treatment unit based on these findings is now available. It is notable among other things for being user-friendly, quick to apply and comfortable to wear. P-STIM™ is ideal for point stimulation on the ear. We recommend stimulating the points according to Somatotopie Nogier. In cases of chronic low-back pain the desired effects are achieved by microstimulation, having selected two general pain points and one local stimulation point on the ear. In cases of prolonged chronic pain we recommend an overall therapy period of 6 weeks. Control tests should be carried out within 6 months to check the success of the therapy using VAS (visual analog pain scale).

List of clinical studies:

1. Biodevices 2009 Conference
2. Dual cell stimulation in woundhealing (Part 1)
3. Dual cell stimulation in woundhealing (Part 2)

This is an additional list of some of the publications related to the treatment with P-STIM™ and the benefits of auricular electrical stimulation.

1. Electrical Stimulation of Auricular Acupuncture Points Is More Effective Than Conventional Manual Auricular Acupuncture in Chronic Cervical Pain: A Pilot Study
2. The Short- and Long-Term Benefit in Chronic Low Back Pain Through Adjuvant Electrical Versus Manual Auricular Acupuncture
3. Objectivation of cerebral effects with a new continuous electrical auricular stimulation technique for pain management
4. Auricular electro-acupuncture as an additional perioperative analgesic method during oocyte aspiration in IVF treatment
5. ADAPTIVE AURICULAR ELECTRICAL STIMULATION CONTROLLED BY VITAL BIOSIGNALS
6. Darstellung des Nervus Vagus am äußeren Ohr
7. EFFECTIVENESS OF THE IS-3™ ON PATIENTS WITH CHRONIC PAIN NOT ASSOCIATED WITH CANCER